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・ Phoradendron leucarpum
・ Phoradendron libocedri
・ Phoradendron macrophyllum
・ Phoradendron madisonii
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・ Phorbol 12,13-dibutyrate
Phorbol-12-myristate-13-acetate-induced protein 1
・ Phorbol-diester hydrolase
・ Phorceful Ahead
・ Phorcidella
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Phorbol-12-myristate-13-acetate-induced protein 1 : ウィキペディア英語版
Phorbol-12-myristate-13-acetate-induced protein 1

Phorbol-12-myristate-13-acetate-induced protein 1 is a protein that in humans is encoded by the ''PMAIP1'' gene, and is also known as Noxa.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5366 )
Noxa (Latin for ''damage'') is a pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members can form hetero- or homodimers, and they act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The expression of Noxa is regulated by the tumor suppressor p53, and Noxa has been shown to be involved in p53-mediated apoptosis.
== Interactions ==
Noxa has been shown to interact with:
* BCL2-like 1,〔
* Bcl-2,〔〔 and
* MCL1.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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