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Phorbol-12-myristate-13-acetate-induced protein 1 is a protein that in humans is encoded by the ''PMAIP1'' gene, and is also known as Noxa.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5366 )〕 Noxa (Latin for ''damage'') is a pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members can form hetero- or homodimers, and they act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The expression of Noxa is regulated by the tumor suppressor p53, and Noxa has been shown to be involved in p53-mediated apoptosis. == Interactions == Noxa has been shown to interact with: * BCL2-like 1,〔 * Bcl-2,〔〔 and * MCL1. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Phorbol-12-myristate-13-acetate-induced protein 1」の詳細全文を読む スポンサード リンク
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